Peer-reviewed veterinary case report
Veterinary anthelmintics: old and new.
- Journal:
- Trends in parasitology
- Year:
- 2004
- Authors:
- McKellar, Quintin A & Jackson, Frank
- Affiliation:
- The Royal Veterinary College · United Kingdom
Plain-English summary
Over the past several decades, there has been significant progress in developing medications to treat parasites in animals, especially between 1960 and 1980 when many effective drugs were created. These advancements helped improve livestock productivity, which was crucial as the human population grew rapidly. In the years since, researchers have focused on refining these existing medications and addressing the growing issue of drug resistance in parasites. Looking ahead, the goal is to create new treatments while learning from past experiences to ensure these new drugs remain effective for a long time. This review highlights important discoveries and developments in the field of veterinary parasite treatments.
Abstract
Between 1960 and 1980, extraordinary success was achieved in anthelmintic development for animals. In these 20 years, drugs with diverse structure, novel activity and enviable safety were produced for a global livestock industry leading to the productivity gains needed to support a human population that grew by 1.5 billion during the same period. The following 20 years have been spent refining existing molecules with niche activity (parasite and host specificity), improving delivery systems and worrying about the inexorable spread of drug resistance. The challenge for the next 20 years will be to use the technologies available to design and produce new drugs and biological controls. Then, to use the lessons of the past to ensure that the new drugs enjoy a longer useful lifespan and contribute to an animal health industry (livestock and companion) which enriches the lives of a global population. Old and new veterinary anthelmintics comprise a very large field, which could not be comprehensively reviewed in a short article. The present mini-review focuses on major chemical discoveries, formulation developments, administration strategies and new products.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15363438/