Peer-reviewed veterinary case report
Vinblastine and prednisolone treatment for dog skin mast cell tumors
By Davies, David R et al.·Published in Journal of the American Animal Hospital Association·2004·Murdoch University, Australia·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Vinblastine and prednisolone as adjunctive therapy for canine cutaneous mast cell tumors.
- Species:
- dog
Plain-English summary
Twenty-seven dogs with skin tumors called mast cell tumors (MCT) that were not completely removed by surgery were treated with a combination of vinblastine and prednisolone, which are chemotherapy drugs. After a year, 14 of the dogs were free of MCT, while a few experienced local recurrence or developed new tumors. Thankfully, there were no deaths directly related to the tumors, although one dog did die from an infection during treatment. Overall, the chemotherapy was mostly well-tolerated with only mild side effects.
People also search for: dog skin tumor treatment · mast cell tumor in dogs · vinblastine for dog cancer · prednisolone side effects in dogs
Abstract
Twenty-seven dogs with inadequately excised, cutaneous mast cell tumors (MCT; 20 residual microscopic disease, seven marginal excision) were treated with a vinblastine and prednisolone chemotherapeutic protocol. Twenty dogs were available for follow-up examination after 12 months. One dog suffered local recurrence of the tumor, four dogs developed new cutaneous tumors, and one dog had both events. Fourteen dogs were free of MCT. There was no confirmed tumor-related mortality. Although toxicity from the chemotherapy was generally mild, one dog died of sepsis during treatment.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15007048/