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Peer-reviewed veterinary case report

Vincristine chemotherapy helped dog and cat with cancer

By Hahn, K A·Published in Journal of the American Veterinary Medical Association·1990·Department of Veterinary Clinical Sciences·View original on PubMed

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Original publication title: Vincristine sulfate as single-agent chemotherapy in a dog and a cat with malignant neoplasms.

Species:
cat

Plain-English summary

A 12-year-old cat and an 11-year-old dog were both diagnosed with serious cancers: the cat had a fibrosarcoma (a type of tumor) in its jaw, and the dog had hemangiosarcoma (a cancer affecting blood vessels) that had spread to the lungs. They were treated with a chemotherapy drug called vincristine sulfate, given weekly through an IV. After three months of treatment, both pets showed no signs of their cancers and were in complete remission. This suggests that vincristine sulfate can be an effective treatment option for these types of tumors in pets.

People also search for: cat fibrosarcoma treatment · dog hemangiosarcoma chemotherapy · vincristine for pets

Abstract

A 12-year-old 4-kg spayed domestic shorthair cat with a poorly differentiated fibrosarcoma of the rostral aspect of the mandible and an 11-year-old 13-kg castrated dog of mixed breeding with pulmonary metastatic hemangiosarcoma were treated with 0.5 mg of vincristine sulfate/m2 of body surface, IV, weekly. Three months after beginning treatment, both animals had complete clinical remission. The role of this vinca alkaloid as a single agent for malignant neoplasms has seldom been discussed in the veterinary scientific literature. The results of these two cases indicate that single-agent vincristine sulfate chemotherapy is effective in the treatment of feline fibrosarcoma and canine hemangiosarcoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2211297/