Peer-reviewed veterinary case report
Viral Vectors for Gene Transfer.
- Journal:
- Current protocols in mouse biology
- Year:
- 2018
- Authors:
- Chen, Yong Hong et al.
- Affiliation:
- The Children's Hospital of Philadelphia · United States
Abstract
Viral vectors are a promising tool for effective delivery of genetic material into cells. They take advantage of the natural ability of a virus to deliver a genetic payload into cells while being genetically modified such that their ability to replicate is crippled or removed. Here, an updated overview of routinely used viral vectors, including adeno-associated viruses (AAV), retroviruses/lentiviruses, and adenoviruses (Ads), is provided, as well as perspectives on their advantages and disadvantages in research and gene therapy. © 2018 by John Wiley & Sons, Inc.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30485696/