Peer-reviewed veterinary case report
Virucidal efficacy of the newer quaternary ammonium compounds.
- Journal:
- Journal of the American Animal Hospital Association
- Year:
- 1995
- Authors:
- Kennedy, M A et al.
- Affiliation:
- Department of Comparative Medicine · United States
Plain-English summary
Researchers looked at how well some newer disinfectants, which contain quaternary ammonium compounds (QACs), can kill certain viruses that affect cats and dogs. They tested these disinfectants against feline herpesvirus, feline calicivirus, and canine parvovirus, using them as directed by the manufacturers and letting them sit for 10 minutes at room temperature. They found that two of the four disinfectants completely killed the feline herpesvirus, while the others reduced its presence but didn't eliminate it. However, none of the disinfectants were effective against feline calicivirus, and they didn't significantly affect canine parvovirus either. In contrast, sodium hypochlorite was effective and completely killed all the viruses tested.
Abstract
The virucidal activity of several disinfectants containing newer generation quaternary ammonium compounds (QACs) as their active ingredients was evaluated. Disinfectants were used at the manufacturers' recommended dilutions with isolates of feline herpesvirus, feline calicivirus, and canine parvovirus, and a contact time of 10 minutes at room temperature. Detoxification of virus/disinfectant solutions was done by dialysis prior to virus assay in cell cultures. Two of four disinfectants completely inactivated feline herpesvirus, and two significantly reduced the titer of this virus. None of the disinfectants that were tested completely inactivated feline calicivirus. Canine parvovirus was not inactivated significantly by any of the QAC disinfectants. Sodium hypochlorite completely inactivated all viruses.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/7634062/