Virucidal multipurpose aqueous solution containing quaternary ammonium cation and sulfobetaine is effective against highly pathogenic avian influenza viruses.

Abstract

Highly pathogenic avian influenza virus (HPAIV) is an enveloped virus currently spreading among birds around the world, and infections in humans have been reported. Common disinfectants such as ethanol and chlorine are somewhat effective, but the development of more effective disinfectants to prevent infection is urgently needed. As a result of a series of studies focusing on cationic antibacterial agents, DEA-171 has been developed as a safe and effective anti-enveloped virus by adding sulfobetaine to a specific quaternary ammonium cation. This solution inactivated approximately 99.0% of H5 HPAIV in 30 min.