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Peer-reviewed veterinary case report

Visualizing the Tumor Microenvironment of Liver Metastasis by Spinning Disk Confocal Microscopy.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2016
Authors:
Babes, Liane & Kubes, Paul
Affiliation:
Department of Physiology and Pharmacology · Canada

Abstract

Intravital microscopy has evolved into an invaluable technique to study the complexity of tumors by visualizing individual cells in live organisms. Here, we describe a method for employing intravital spinning disk confocal microscopy to picture high-resolution tumor-stroma interactions in real time. We depict in detail the surgical procedures to image various tumor microenvironments and different cellular components in the liver.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/27581024/