Peer-reviewed veterinary case report
Vitamin C for neuroprotection in neonatal encephalopathy.
- Journal:
- Pediatric research
- Year:
- 2025
- Authors:
- Chavez-Valdez, Raul et al.
- Affiliation:
- Department of Pediatrics · United States
- Species:
- rodent
Abstract
In this commentary, we provide additional context to interpret the findings reported on the manuscript by Liu et al., "Neuroprotective effects of vitamin C on hypoxic-ischemic brain injury in neonatal mice" published in this issue of Pediatric Research. IMPACT: Vitamin C is an anti-oxidant with anti-inflammatory effects, which may be neuroprotective against neonatal hypoxic-ischemic (HI) brain injury in a preterm mouse model Several experimental caveats include the timing of intervention, model use and side effects. We provide additional context to the reader in the interpretation of the data.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/40467978/