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Peer-reviewed veterinary case report

Vitamin K deficiency causing blood clotting issues in Devon Rex cats

By Maddison, J E et al.·Published in Journal of the American Veterinary Medical Association·1990·Department of Veterinary Clinical Sciences, Australia·View original on PubMed

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Original publication title: Vitamin K-dependent multifactor coagulopathy in Devon Rex cats.

Species:
cat
Stomach & digestionCats

Plain-English summary

Three Devon Rex cats were diagnosed with a bleeding disorder caused by a lack of vitamin K, which is essential for proper blood clotting. The cats showed no signs of liver or gastrointestinal issues, and there was no indication they had ingested any harmful substances. After starting oral vitamin K1 treatment, their blood clotting levels returned to normal. However, when the treatment was stopped for two of the cats, their clotting times became prolonged again, although they did not show any symptoms of bleeding.

People also search for: Devon Rex cat bleeding disorder · vitamin K deficiency in cats · cat blood clotting treatment

Abstract

A coagulopathy attributable to a deficiency of vitamin K-dependent clotting factors (II, VII, IX, and X) was diagnosed in 3 Devon Rex cats. There was no evidence for exposure to vitamin-antagonist-related rodenticides. The cats did not have evidence of hepatic disease, gastrointestinal disease, or fat malassimilation. Oral treatment with vitamin K1 resulted in normalization of clotting factor concentrations. However, when treatment was discontinued in 2 cats, prothrombin and activated partial thromboplastin values became prolonged again, although the cats did not have clinical signs of a bleeding disorder.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2272883/