Peer-reviewed veterinary case report
Weekly plant extract shampoo plus lokivetmab for dog skin allergy
By Bensignor, Emmanuel & Videmont, Emilie·Published in Veterinary Dermatology·2021·Dermatology Service Oniris, Nantes Veterinary School Nantes 44307 France, France·View original on Crossref →
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Original publication title: Weekly topical therapy based on plant extracts combined with lokivetmab in canine atopic dermatitis
- Species:
- dog
Plain-English summary
A group of 30 dogs with atopic dermatitis (a skin allergy) received either a single injection of lokivetmab or the same injection along with a weekly topical treatment using a special shampoo and spot-on product. The dogs that received both treatments showed significantly better improvement in itching and skin condition compared to those who only got the injection. Not only did the combined treatment help reduce symptoms faster, but it also provided longer-lasting relief from flare-ups. This suggests that using topical therapies alongside lokivetmab can be beneficial for dogs suffering from skin allergies.
People also search for: dog itching treatment · atopic dermatitis in dogs · lokivetmab and shampoo for dogs
Abstract
BackgroundLokivetmab is an effective treatment for atopic dermatitis (AD) in dogs. The aim of this prospective study was to determine if topical products containing plant extracts could enhance the clinical efficacy of lokivetmab.AnimalsThirty atopic dogs were included.Methods and materialsDogs were allocated randomly to be treated either with a single injection of lokivetmab (mean dose 1.34 mg/kg; Group A) or to a single injection (mean dose 1.28 mg/kg) coupled with a weekly topical treatment using a shampoo and a spot‐on specifically designed to improve skin barrier defect (Group B). Clinical parameters evaluated included pruritus (pruritus Visual Analog Scale) and skin lesions (Canine Atopic Dermatitis Lesion Index, CADLI); cosmetic evaluation, and owner and investigator global assessment of efficacy (OGATE) also were carried out. Dogs were re‐examined after 10, 17 and 31 days, and until a clinical relapse occurred.ResultsAn improvement was noted for all dogs, with scores being significantly better in dogs in Group B than in those in Group A; after 10 days for cosmetic evaluation, 17 days for pruritus (P = 0.039) and OGATE, and 31 days for CADLI (P = 0.043). A longer‐lasting remission was noted in Group B compared to Group A; dogs receiving the combined treatment showed an extended time to flare compared to dogs treated with lokivetmab alone (P = 0.012).Conclusions and clinical importanceThis study suggests that combining lokivetmab with topical therapies designed to repair the skin barrier potentially have value in the treatment of AD in dogs.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/vde.13004