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Peer-reviewed veterinary case report

What is a schizophrenic mouse?

Journal:
Neuron
Year:
2007
Authors:
Low, Nancy C & Hardy, John
Affiliation:
Department of Psychiatry · Canada
Species:
rodent

Abstract

In this issue of Neuron, Clapcote et al. examine mice containing missense mutations of the DISC1 gene, a locus associated with major mental illness in at least one large Scottish family. Genetic manipulation of mouse homologs of genes implicated in the etiology of psychiatric disorders is a promising avenue of research, but also one that is fraught with interpretative difficulties.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17481386/