Peer-reviewed veterinary case report
Blood test shows rare cancer cells in 10-year-old mixed-breed dog
By Peres, Laura S et al.·Published in Veterinary clinical pathology·2026·Department of Veterinary Clinical Pathology, Brazil·View original on PubMed →
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Original publication title: What Is Your Diagnosis? Blood Smear From a Mixed-Breed Dog.
- Species:
- dog
Plain-English summary
A 10-year-old spayed female mixed-breed dog was brought to the vet because she had not been eating for a week and had a fever. Blood tests showed unusual cells that made the vet suspect a serious condition. Further tests on her spleen confirmed she had hemophagocytic histiocytic sarcoma, a type of cancer. This diagnosis indicated that the cancer had spread throughout her body.
People also search for: dog not eating fever · mixed-breed dog cancer symptoms · hemophagocytic histiocytic sarcoma treatment
Abstract
A 10-year-old spayed female mixed-breed dog was presented with a one-week history of inappetence and hyperthermia. Blood smear evaluation revealed the presence of rare atypical cells, raising suspicion for a circulating neoplasm. Spleen cytology, histopathology, and immunohistochemistry confirmed the diagnosis of hemophagocytic histiocytic sarcoma. The morphologic similarity between the atypical cells observed in the blood smear and those identified in the splenic cytology strongly suggests systemic dissemination of the disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/42099195/