Peer-reviewed veterinary case report
Whole mitochondrial genome sequence for an osteoarthritis model of Guinea pig (Caviidae; Cavia).
- Journal:
- Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis
- Year:
- 2016
- Authors:
- Cui, Xin-Gang et al.
- Affiliation:
- a Department of Spine · China
- Species:
- rodent
Abstract
Animal models played an important role in osteoarthritis studies. Here, the complete mitochondrial genome sequence of the Guinea pig was reported for the first time. The total length of the mitogenome was 16,797 bp. It contained the typical structure, including two ribosomal RNA genes, 13 protein-coding genes, 22 transfer RNA genes and one non-coding control region (D-loop region). The overall composition of the mitogenome was estimated to be 34.9% for A, 26.1% for T, 26.0% for C and 13.0% for G showing an A-T (61.0%)-rich feature. This mitochondrial genome sequence will provide new genetic resource into osteoarthritis disease.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25541309/