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Peer-reviewed veterinary case report

World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) guidelines for evaluating the efficacy of parasiticides for the treatment, prevention and control of flea and tick infestation on dogs and cats.

Journal:
Veterinary parasitology
Year:
2007
Authors:
Marchiondo, A A et al.
Affiliation:
IVX Animal Health Inc. · United States

Plain-English summary

These guidelines are designed to help researchers and veterinarians evaluate how well treatments for fleas and ticks work on dogs and cats. The treatments being studied include products that kill these pests and those that prevent them from growing or reproducing. The guidelines cover important aspects like choosing the right animals for testing, figuring out the correct doses, and keeping accurate records of the results. They also aim to help authorities who approve new flea and tick treatments and promote consistent practices around the world. Overall, these guidelines are meant to ensure that treatments are effective and safe for pets.

Abstract

These guidelines are intended to assist the planning and conduct of laboratory and clinical studies to assess the efficacy of ectoparasiticides applied to dogs or cats for the purpose of treating, preventing and controlling flea and tick infestations. The term ectoparasiticide includes insecticidal and acaricidal compounds, as well as insect growth regulators. The range of biological activities accruing from animal treatment that are considered include: repellency and anti-feeding effects, knockdown, speed of kill, immediate and persistent lethal effects, and interference with egg fertility and subsequent development of off-host life cycle stages. Information is provided on the selection of animals, dose determination, dose confirmation and field studies, record keeping, interpretation of results and animal welfare. These guidelines are also intended to assist registration authorities involved in the approval and registration of new parasiticides, and to facilitate the worldwide adoption of harmonized procedures.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17140735/