Peer-reviewed veterinary case report
X-linked severe combined immunodeficiency in a family of Cardigan Welsh corgis.
- Journal:
- Journal of the American Animal Hospital Association
- Year:
- 1997
- Authors:
- Pullen, R P et al.
- Affiliation:
- School of Veterinary Medicine · United States
- Species:
- dog
Abstract
Two, male, Cardigan Welsh corgi puppies, one of which was diagnosed with X-linked severe combined immunodeficiency (XSCID), are described in this report. The first puppy was euthanized before definitive immunological testing could be performed. When the second puppy was presented and the relationship between the two was discovered, immunological testing was pursued immediately due to this puppy's rapid deterioration. The immunological test results and genetic studies were compared to the XSCID basset hounds and found to be similar. By unveiling the mutation, the pedigree could be analyzed and the carrier females removed from the breeding population.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/9358416/