Peer-reviewed veterinary case report
β-TCP versus autologous bone for repair of alveolar clefts in a goat model.
- Journal:
- The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
- Year:
- 2011
- Authors:
- de Ruiter, Ad et al.
Abstract
OBJECTIVE: The aim of this study in goats was to test the hypothesis that a novel synthetic bone substitute beta tricalcium phosphate (β-TCP) can work as well as autologous bone harvested from the iliac crest for grafting and repair of alveolar clefts. DESIGN: Ten adult Dutch milk goats (Capra hircus) were used in a split-mouth study design. MAIN OUTCOME MEASURES: Volumetric histologic assessment of new bone formation and radiographic measurement of orthodontic movement of teeth in a formerly created alveolar cleft. CONCLUSIONS: The synthetic bone substitute β-TCP was shown to result in bone healing similar to that of iliac crest bone. The surgical, orthodontic, and histologic results now warrant the testing of β-TCP in the human cleft situation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20815732/