Peer-reviewed veterinary case report
Cat with blocked ureters from xanthine bladder stones at 10 months
By Mestrinho, Lisa A et al.·Published in Journal of feline medicine and surgery·2013·Faculty of Veterinary Medicine·View original on PubMed →
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Original publication title: Xanthine urolithiasis causing bilateral ureteral obstruction in a 10-month-old cat.
- Species:
- cat
Plain-English summary
A 10-month-old female domestic shorthair cat was brought to the vet with acute kidney failure caused by a blockage in both ureters due to xanthine stones. Despite initial medical treatment, the blockage did not improve, so the vet performed surgery to remove the stones. After the surgery, the cat recovered well, and her kidney function returned to normal within a week. At a follow-up a year later, she showed no symptoms, but ultrasound revealed small stones still present in her kidneys. This case suggests she may have a genetic condition that causes her body to produce these stones.
People also search for: cat kidney stones treatment · xanthine urolithiasis in cats · cat acute kidney failure symptoms
Abstract
Xanthine urolithiasis was diagnosed in a 10-month-old intact female domestic shorthair cat presented with acute renal failure due to bilateral ureteral obstruction. Ultrasonography revealed the presence of multiple uroliths in both kidneys and ureters that were not detectable on previous survey radiographs. Medical management failed and ureteral obstruction persisted with no evidence of stone migration into the bladder. Bilateral ureterotomy with urolith removal was performed in order to relieve the obstruction. The cat recovered from surgery, and blood urea nitrogen and creatinine values decreased within normal limits 6 days postoperatively. Urolith analysis by infrared spectrometry determined xanthine composition, and a higher blood and urine concentration of hypoxanthine and xanthine was also found. At 1-year follow-up, the cat was free of clinical signs. However, ultrasonography of the abdomen revealed small-size calculi in both kidneys, despite the low protein diet intake. The very young age of the animal suggests a possible congenital xanthinuria.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23413269/