Peer-reviewed veterinary case report
¹⁸F-FDG and ¹¹C-MET positron emission tomography findings of cutaneous mast cell tumor in a dog.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2011
- Authors:
- Kang, Byeong-Teck et al.
- Affiliation:
- National Institute of Neurological Disorders and Stroke · United States
- Species:
- dog
Abstract
A 12-year-old intact male Maltese dog presented with an inguinal mass. Histopathology revealed a grade III mast cell tumor. Computed tomography demonstrated pulmonary and inguinal nodules and masses. Chemotherapy was performed using a vinblastine/prednisone protocol, and the inguinal mass disappeared 5 weeks later. Use of 2-deoxy-2-[¹⁸F]fluoro-D-glucose (¹⁸F-FDG) and (L)-[methyl- ¹¹C]methionine (¹¹C-MET)-positron emission tomography (PET) demonstrated hypermetabolic areas in the lungs and inguinal region one week after initial chemotherapy. The standardized uptake values of ¹⁸F-FDG were not different between lung and inguinal lesions; however, the inguinal lesion had a higher ¹¹C-MET standardized uptake value than the lung lesions. The hypermetabolic area was still visible on the second ¹⁸F-FDG-PET scan despite the disappearance of the mass. This is the first report of ¹¹C-MET-PET findings associated with a cutaneous mast cell tumor in a dog.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20962463/