Peer-reviewed veterinary case report
PET scan shows lung and groin tumors in dog with mast cell cancer
By Kang, Byeong-Teck et al.·Published in The Journal of veterinary medical science·2011·National Institute of Neurological Disorders and Stroke, United States·View original on PubMed →
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Original publication title: ¹⁸F-FDG and ¹¹C-MET positron emission tomography findings of cutaneous mast cell tumor in a dog.
- Species:
- dog
Plain-English summary
A 12-year-old male Maltese dog was brought in with a mass in the groin area. After testing, the mass was identified as a grade III mast cell tumor, which is a type of skin cancer. The dog underwent chemotherapy with vinblastine and prednisone, and the mass disappeared after five weeks. However, imaging tests showed that there were still active areas in the lungs and groin, indicating that the cancer was still present in those areas despite the mass being gone. This case highlights the importance of ongoing monitoring even after treatment for skin tumors.
People also search for: dog inguinal mass treatment · Maltese mast cell tumor chemotherapy · dog skin cancer symptoms
Abstract
A 12-year-old intact male Maltese dog presented with an inguinal mass. Histopathology revealed a grade III mast cell tumor. Computed tomography demonstrated pulmonary and inguinal nodules and masses. Chemotherapy was performed using a vinblastine/prednisone protocol, and the inguinal mass disappeared 5 weeks later. Use of 2-deoxy-2-[¹⁸F]fluoro-D-glucose (¹⁸F-FDG) and (L)-[methyl- ¹¹C]methionine (¹¹C-MET)-positron emission tomography (PET) demonstrated hypermetabolic areas in the lungs and inguinal region one week after initial chemotherapy. The standardized uptake values of ¹⁸F-FDG were not different between lung and inguinal lesions; however, the inguinal lesion had a higher ¹¹C-MET standardized uptake value than the lung lesions. The hypermetabolic area was still visible on the second ¹⁸F-FDG-PET scan despite the disappearance of the mass. This is the first report of ¹¹C-MET-PET findings associated with a cutaneous mast cell tumor in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20962463/