Peer-reviewed veterinary case report
Can my anemic cat safely receive dog blood?
By Euler, Catharina C et al.·Published in Veterinary clinical pathology·2016·School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Xenotransfusion of anemic cats with blood compatibility issues: pre- and posttransfusion laboratory diagnostic and crossmatching studies.
Plain-English summary
Two anemic cats received blood transfusions from dogs because their own blood types were incompatible. One cat had type AB blood and the other had type A blood and experienced a severe reaction to a previous transfusion. After receiving the dog blood, both cats showed temporary improvement, but their condition worsened due to a serious reaction that caused their red blood cells to break down quickly. Although both cats survived the procedure, the dog blood did not last long in their systems, and the tests showed mixed compatibility results between the cat and dog blood types.
People also search for: cat anemia treatment · dog blood transfusion for cats · feline blood type compatibility
Abstract
BACKGROUND: Finding compatible feline blood donors can be challenging. Canine blood has been occasionally used when compatible feline blood was not available in emergency situations. OBJECTIVES: The study goals were to describe the effects of xenotransfusion in 2 anemic cats receiving canine blood because of discordant blood types and acute transfusion reaction, respectively, and to report in vitro heterotyping and crossmatching results between canine and feline blood samples. MATERIAL AND METHODS: Blood samples from patients and other cats and dogs were typed, crossmatched, and assessed for alloantibodies using gel, card, and immunochromatographic strip techniques. RESULTS: Cat 1 was found to have type AB blood. Cat 2, which experienced an acute transfusion reaction, had type A blood. Neither had detectable alloantibodies against feline RBC. Both cats transiently improved after transfusion with canine blood; however, acute intravascular hemolysis occurred and the PCV rapidly declined. Blood typing post xenotransfusion with DEA 1 strips revealed a positive control band that was absent in feline blood, thus allowing for the identification of transfused canine RBC. Longitudinal assessment revealed that canine RBC could no longer be detected 4 days after xenotransfusion. Major crossmatching (feline plasma with canine RBC) resulted in both positive and negative reactions, depending on the cat. Minor crossmatching results showed mostly incompatibility. CONCLUSION: While both cats survived xenotransfusion, the positive control band on the DEA 1 strip revealed that transfused canine RBC were short-lived and intravascular hemolysis occurred. Crossmatch results between cats and dogs showed varied incompatibilities and may not predict transfusion reactions.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27243621/