Peer-reviewed veterinary case report
Year-round tick protection in dogs from one fluralaner injection
By Fisara, Petr & Guerino, Frank·Published in Parasites & vectors·2023·MSD Animal Health Australia Ltd., Australia·View original on PubMed →
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Original publication title: Year-round efficacy of a single treatment of fluralaner injectable suspension (Bravecto Quantum) against repeated infestations with Ixodes holocyclus in dogs.
- Species:
- dog
Plain-English summary
A group of healthy dogs was treated with a single injection of fluralaner (Bravecto Quantum) to protect against tick infestations from the Ixodes holocyclus tick, which can cause serious health issues like tick paralysis. The treatment showed impressive results, providing up to a full year of protection against new tick infestations, with effectiveness ranging from 95.7% to 100% in the months following the injection. No side effects were reported, making it a safe option for pet owners looking to keep their dogs tick-free. This long-lasting protection can help ensure that dogs remain safe from potentially dangerous tick bites.
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Abstract
BACKGROUND: The longer the duration of protection of an acaricide against canine infestation with Ixodes holocyclus, the lower the risk of gaps in tick control programs that will place dogs at risk of potentially fatal tick-induced paralysis. Two studies investigated the duration of efficacy provided by a novel injectable suspension of fluralaner (Bravecto Quantum) against this tick species. METHODS: In both studies, 20 clinically healthy dogs were randomized to an untreated control group or to a group treated once, on Day 0, with the injectable fluralaner suspension (15 mg/kg). Dogs were infested with up to 25 unfed adult female I. holocyclus ticks on Day -1, during Weeks 1 and 2, and then at intervals no greater than approximately 3 months for the 13 months following treatment. Ticks were assessed in situ at 24 and 48 h and assessed and removed at 72 h following treatment and each subsequent infestation. Efficacy was determined by comparing arithmetic mean live tick (attached or free) counts in the treated group with the control group. RESULTS: The untreated control dogs maintained adequate infestations for efficacy evaluations at all assessment weeks, with mean tick counts ranging from 16.2 to 21.6 in Study 1 and 14.0 to 23.5 in Study 2. The efficacy of fluralaner injectable suspension against existing infestations, determined 72 h following treatment administration, was 64.1% in Study 1 and 42.7% in Study 2. Efficacy against post-treatment infestations in Study 1 ranged from 95.7 to 100% from Week 1 through Week 57; in Study 2 efficacy was 100% at every assessment from Week 1 through Week 57. No treatment-related adverse events were recorded in either study. CONCLUSION: The injectable fluralaner suspension was highly effective against I. holocyclus infestations of dogs from one week through 13 months following a single treatment. By placing treatment with the veterinarian, killing ticks within 72 h of attachment, and providing a full year of protection, fluralaner injectable suspension can help facilitate owner compliance with tick control treatment recommendations, thus reducing the risk of canine tick paralysis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37864235/