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Peer-reviewed veterinary case report

Pug dog with seizures and brain atrophy from necrotizing

By Kitagawa, Masato et al.·Published in The Journal of veterinary medical science·2007·Department of Veterinary Medicine, Japan·View original on PubMed

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Original publication title: A canine case of necrotizing meningoencephalitis for long-term observation: clinical and MRI findings.

Species:
dog

Plain-English summary

A 3-year-old female pug had a seizure followed by other neurological issues like confusion and muscle twitching over the next four years. As her condition progressed, she became unable to stand and showed signs of dementia. An MRI revealed brain shrinkage, and tests confirmed she had necrotizing meningoencephalitis, a serious brain inflammation. Unfortunately, despite observation and care, her condition worsened until her passing.

People also search for: pug seizure treatment · dog brain inflammation symptoms · why is my dog confused and twitching

Abstract

A 3-year-old female pug presented with general seizure following a partial seizure. During the remaining 48 months till death, the dog showed various neurological signs such as disturbance of consciousness, myoclonus and various types of partial seizure after each occurrence of the seizure clusters, and the dog eventually exhibited inability to stand and dementia. Magnetic resonance imaging findings revealed atrophy of the brain over the course of the disease. On histopathological analysis, the dog was diagnosed with necrotizing meningoencephalitis. This case of a canine necrotizing meningoencephalitis observed over the long term is valuable.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18057839/