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Peer-reviewed veterinary case report

Dog with skin lymphoma and treatment results

By SARIDOMICHELAKIS (Μ. Ν. ΣΑΡΙΔΟΜΙΧΕΛΑΚΗΣ), M. N. et al.·Published in Journal of the Hellenic Veterinary Medical Society·2018·View original on Crossref

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Original publication title: A case of canine epitheliotropic lymphoma (mycosis fungoides)

Species:
dog
LymphomaSkin & coatDogs

Plain-English summary

A 13-year-old male mongrel dog was brought to the vet with skin problems, specifically non-itchy lesions that had been present for five months. The vet diagnosed him with epitheliotropic lymphoma, a type of skin cancer, after examining skin samples. Initially, a treatment with isotretinoin didn’t help much, but a combination of chemotherapy with Lasparaginase and isotretinoin led to significant improvement in his skin condition. Unfortunately, the dog later experienced depression and loss of appetite, and he passed away 15 months after the skin lesions first appeared.

People also search for: dog skin cancer treatment · epitheliotropic lymphoma in dogs · non-itchy skin lesions in dogs

Abstract

The clinical picture, diagnosis and treatment of a dog with epitheliotropic lymphoma are presented. The dog (male, mongrel, 13-year old) was admitted to our Clinic with a 5-month history of non-pruritic skin lesions. At clinical examination a multifocal to diffuse exfoliative erythrodermia was the most striking finding. Diagnosis of epitheliotropic lymphoma was based on cutaneous histopathology, revealing a dense dermal and epidermal lymphocytic infiltration and Pautrie microabcess formation. Initial treatment with isotretinoin had a poor impact on skin lesions that progressed to the macular stage. On the contrary, combination chemotherapy with Lasparaginase and isotretinoin resulted in substantial improvement. The animal died, following a short period of depression and inappetance, 15 months after the first appearance of skin lesions and 10 months after diagnosis.

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Original publication on Crossref: https://doi.org/10.12681/jhvms.15459