Peer-reviewed veterinary case report
A case of canine gastrinoma.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2004
- Authors:
- Fukushima, Ryuji et al.
- Affiliation:
- Veterinary ME Research Center · Japan
- Species:
- dog
Plain-English summary
This case involves a 10-year-old Shih Tzu that was experiencing severe vomiting, diarrhea, and had stopped eating. When the veterinarian looked inside the dog's stomach using a camera (endoscopy), they found some unclear areas and narrowing in the stomach and some swelling in the intestine. An ultrasound of the pancreas showed some unusual shadows, leading the vet to check the dog's blood for gastrin, a hormone that can indicate a specific type of tumor. The blood test showed high levels of gastrin, and a further examination after the dog passed away confirmed that the pancreatic cells were producing this hormone, leading to a diagnosis of pancreatic gastrinoma.
Abstract
The dog of this case was a 10-year-old Shih Tzu with refractory vomiting, diarrhea and anorexia. Endoscopy revealed an unclear at gastric angle, a stenosis at pyloric antrum and congestion in duodenal mucosa. Since abnormal shadows of irregular echo-levels were disclosed by pancreas ultrasonography, serum gastrin level was determined with a suspect of gastrinoma. And an increase of serum gastrin was demonstrated. In addition, postmortem histological examination revealed that the pancreatic cells were positive for gastrin. Based on these findings, the dog was diagnosed as pancreatic gastrinoma.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15353855/