Peer-reviewed veterinary case report
Cat develops injection-site sarcoma after cisplatin chemotherapy
By Martano, Marina et al.·Published in Journal of Feline Medicine and Surgery·2012·School of Veterinary Medicine, Italy, Italy·View original on Crossref →
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Original publication title: A case of feline injection-site sarcoma at the site of cisplatin injections
- Species:
- cat
Plain-English summary
A 14-year-old spayed female domestic shorthair cat developed a new tumor at the site of chemotherapy injections for a nasal cancer. After receiving intralesional chemotherapy with cisplatin, a soft tissue sarcoma appeared on her eyelid. Despite having the tumor surgically removed, it came back after 10 months. Unfortunately, the cat was euthanized later, but there were no signs of the cancer spreading to her lungs or lymph nodes. This case suggests that the tumor may have been linked to the injection site.
People also search for: cat eyelid tumor treatment · injection site sarcoma in cats · cisplatin side effects in cats
Abstract
A spayed 14-year-old female domestic shorthair cat presented with a squamous cell carcinoma of the nasal planum and was treated with intralesional chemotherapy. During nasal infiltrations with cisplatin mixed with the cat’s own serum, a new carcinomatous lesion developed at the medial canthus of the right eye, which was also treated using intralesional chemotherapy. Two months after the treatment course, the cat developed a new mass at the site of the eyelid chemotherapy, which was diagnosed as a soft tissue sarcoma. At the owner’s request, the tumour was marginally excised, but it recurred after 10 months. No lung or lymph node metastases were evident at the time of euthanasia. The histotype of the tumour, the coincidence with injections and the histological description make the hypothesis of an injection-site sarcoma likely. To the authors’ knowledge, this is the first case of an injection-site sarcoma at the site of a cisplatin injection.
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Search related cases →Original publication on Crossref: https://doi.org/10.1177/1098612x12449407