Peer-reviewed veterinary case report
Dog with tongue lymphoma improved after oclacitinib treatment
By Nishimori, Shohei et al.·Published in The Journal of veterinary medical science·2025·Jiyugaoka Animal Clinic, Japan·View original on PubMed →
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Original publication title: A case of lingual lymphoma in a dog treated with oclacitinib.
- Species:
- dog
Plain-English summary
A 7-year-old spayed female toy poodle was brought in with a red, swollen mass on her tongue. After a biopsy and tests, the vet diagnosed her with a rare type of lymphoma affecting the tongue. Although there isn't a standard treatment for this condition, the dog showed improvement after being given oclacitinib, a medication typically used for skin allergies in dogs. This case highlights a successful treatment approach without the need for traditional cancer therapies.
People also search for: dog tongue lump treatment · toy poodle lymphoma · oclacitinib for dog cancer · swollen tongue in dogs · dog cancer treatment options
Abstract
Lingual canine T-zone lymphoma (TZL) is a rare form of extranodal canine lymphoma. Seven-years and 5 months old, spayed female toy poodle presented with a red swollen mass on the tongue. A punch biopsy of the lesion was conducted, followed by histopathological and immunohistochemical analyses. Despite the absence of a lymph node excisional biopsy, the case was diagnosed as canine lingual TZL. Although there is no established treatment for lingual TZL, treatment often follows TZL protocols. In this case, the tongue lesion improved after the administration of oclacitinib, a drug approved for canine atopic dermatitis. We present this case due to its successful management with oclacitinib, without the use of conventional anticancer therapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40189254/