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Peer-reviewed veterinary case report

A case of lingual lymphoma in a dog treated with oclacitinib.

Journal:
The Journal of veterinary medical science
Year:
2025
Authors:
Nishimori, Shohei et al.
Affiliation:
Jiyugaoka Animal Clinic · Japan
Species:
dog

Abstract

Lingual canine T-zone lymphoma (TZL) is a rare form of extranodal canine lymphoma. Seven-years and 5 months old, spayed female toy poodle presented with a red swollen mass on the tongue. A punch biopsy of the lesion was conducted, followed by histopathological and immunohistochemical analyses. Despite the absence of a lymph node excisional biopsy, the case was diagnosed as canine lingual TZL. Although there is no established treatment for lingual TZL, treatment often follows TZL protocols. In this case, the tongue lesion improved after the administration of oclacitinib, a drug approved for canine atopic dermatitis. We present this case due to its successful management with oclacitinib, without the use of conventional anticancer therapy.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/40189254/