Peer-reviewed veterinary case report
Miniature Schnauzer dog with male tumors and fluid-filled uterus due
By Matsuu, Aya et al.·Published in The Journal of veterinary medical science·2009·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: A case of persistent Müllerian duct syndrome with sertoli cell tumor and hydrometra in a dog.
- Species:
- dog
Plain-English summary
A 10-year-old Miniature Schnauzer was brought to the vet because of a swollen abdomen. During surgery, the vet found two tumors and a fluid-filled structure that resembled a uterus. Tests confirmed the dog had Sertoli cell tumors and a condition called hydrometra (fluid in the uterus), linked to a rare genetic issue known as persistent Müllerian duct syndrome, which affects male reproductive development. The dog was diagnosed and treated for these conditions, but the abstract does not specify the outcome of the treatment.
People also search for: Miniature Schnauzer abdominal swelling · dog Sertoli cell tumor treatment · persistent Müllerian duct syndrome in dogs
Abstract
A 10-year-old Miniature Schnauzer with bilateral cryptorchidism and male external genitalia was referred with a history of abdominal enlargement. Upon exploratory laparotomy, two tumors and a connecting structure similar to fluid-filled uterus were recognized. After cytological and bacterial examinations of the fluid and histological examination, this dog was diagnosed with bilateral Sertoli cell tumor with hydrometra. The karyotype of this dog was 78, XY and the sry gene was detected positive by PCR. We diagnosed this dog as a case of persistent Müllerian duct syndrome (PMDS), which is male pseudohermaphroditism. This is the first report regarding the incidence of PMDS in Miniature Schnauzers in Japan, and it suggests the involvement of a gene carrier.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19346713/