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Peer-reviewed veterinary case report

Male Miniature Schnauzer with persistent female organs and testicular

By Aya Matsuu et al.·Published in Journal of Veterinary Medical Science·2009·View original on Semantic Scholar

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Original publication title: A case of persistent Müllerian duct syndrome with sertoli cell tumor and hydrometra in a dog.

Species:
dog

Plain-English summary

A 10-year-old Miniature Schnauzer was brought in with a swollen abdomen and had male genitalia despite having undescended testicles. During surgery, the vet found two tumors and a fluid-filled structure resembling a uterus. Tests confirmed the dog had a type of tumor called a Sertoli cell tumor and a condition known as hydrometra (fluid in the uterus), linked to a rare genetic condition called persistent Müllerian duct syndrome. This case highlights a unique genetic issue in this breed, but specific treatment details and the dog's recovery were not provided.

People also search for: Miniature Schnauzer abdominal swelling · dog Sertoli cell tumor treatment · persistent Müllerian duct syndrome in dogs

Abstract

A 10-year-old Miniature Schnauzer with bilateral cryptorchidism and male external genitalia was referred with a history of abdominal enlargement. Upon exploratory laparotomy, two tumors and a connecting structure similar to fluid-filled uterus were recognized. After cytological and bacterial examinations of the fluid and histological examination, this dog was diagnosed with bilateral Sertoli cell tumor with hydrometra. The karyotype of this dog was 78, XY and the sry gene was detected positive by PCR. We diagnosed this dog as a case of persistent Müllerian duct syndrome (PMDS), which is male pseudohermaphroditism. This is the first report regarding the incidence of PMDS in Miniature Schnauzers in Japan, and it suggests the involvement of a gene carrier.

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Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/19346713