Peer-reviewed veterinary case report
Cat with nasal lymphoma on chemo developed lung toxoplasmosis nodules
By Murakami, Mami et al.·Published in The Journal of veterinary medical science·2018·Joint Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: A case of pulmonary toxoplasmosis resembling multiple lung metastases of nasal lymphoma in a cat receiving chemotherapy.
- Species:
- cat
Plain-English summary
An 11-year-old cat with nasal discharge and watery eyes was diagnosed with nasal lymphoma and started chemotherapy. While the treatment initially seemed effective, a CT scan later revealed enlarged lung nodules caused by a Toxoplasma gondii infection, not cancer spread. After stopping chemotherapy, the cat was treated with clindamycin for the toxoplasmosis, but unfortunately, it later developed kidney lymphoma and passed away. This case highlights that cats undergoing chemotherapy may be at risk for infections like toxoplasmosis, which can mimic cancer symptoms.
People also search for: cat nasal discharge treatment · toxoplasmosis in cats · cat lymphoma chemotherapy side effects
Abstract
An 11-year-old cat presented with nasal discharge and lacrimation and was diagnosed with nasal lymphoma. Although the cat showed favorable progression after undergoing chemotherapy, CT imaging demonstrated enlarged pulmonary nodules caused by Toxoplasma gondii. Following the cessation of chemotherapy, the cat was prescribed clindamycin hydrochloride for toxoplasmosis treatment; however, the cat developed kidney lymphoma and died. No T. gondii organisms were observed in the whole body necropsy specimens. It is known that immunocompromised human patients, including those who undergo chemotherapy, are considered at risk for toxoplasmosis. However, the risk of developing toxoplasmosis in cats undergoing chemotherapy is currently unknown. Findings from this case report suggest that cats with chemotherapy-resistant pulmonary masses might have a T. gondii infection rather than metastatic disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30404954/