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Peer-reviewed veterinary case report

Dog with acute myelomonocytic leukemia treated with chemotherapy

By Hisasue, Masaharu et al.·Published in The Journal of veterinary medical science·2008·Azabu University, Japan·View original on PubMed

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Original publication title: A dog with acute myelomonocytic leukemia.

Species:
dog
LymphomaStomach & digestionDogs

Plain-English summary

A three-year-old dog was brought in with swollen lymph nodes, diarrhea, and a high white blood cell count. Tests revealed that the dog had myelomonocytic leukemia, a type of blood cancer. Despite receiving a combination of chemotherapy and vitamin K2 treatment, the dog unfortunately passed away 47 days after being admitted. This case is notable as it is the first report of this specific type of leukemia in Japan.

People also search for: dog leukemia symptoms · dog swollen lymph nodes treatment · dog diarrhea and high white blood cell count

Abstract

A three-year-old dog with marked leukocytosis, lymphadenopathy, and diarrhea showed an increase in unidentified blasts in the peripheral blood, and they were proliferated in the bone marrow. The dog was diagnosed with myelomonocytic leukemia (M4) because the blast cells were demonstrated by cytochemical staining to be both myeloid and monocytic cells. Although the dog was treated with a multi-combination chemotherapy and induction therapy using vitamin K2, it died on day 47 after the first admission. This case is the first report of M4 in Japan.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18628605/