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Peer-reviewed veterinary case report

Dog with chronic myelomonocytic leukemia and anemia case

By Hiraoka, Hiroko et al.·Published in The Journal of veterinary medical science·2007·Faculty of Agriculture, Japan·View original on PubMed

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Original publication title: A dog with myelodysplastic syndrome: chronic myelomonocytic leukemia.

Species:
dog
LymphomaBreathing & coughDogs

Plain-English summary

An 11-year-old female pug was brought to the vet because she was very anemic and had low platelet counts. Blood tests showed abnormal cells, indicating a serious condition. Unfortunately, despite further testing, including a bone marrow examination, the pug passed away. The tests confirmed she had myelodysplastic syndrome with chronic myelomonocytic leukemia, a type of blood cancer. Sadly, there was no successful treatment for her condition.

People also search for: pug anemia symptoms · dog blood cancer treatment · myelodysplastic syndrome in dogs

Abstract

An eleven-year-old female pug was referred to Yamaguchi University Animal Hospital for evaluation of anemia and thrombocytopenia. The cytological examination of the peripheral blood showed some giant monocytic lineage blast cells. A few granulocytes and platelets had dysplastic features. On day 7, in addition to increasing the monocytic lineage cells, the dysplastic features of the blood had also increased compared to the initial examination. We performed bone marrow aspiration upon her death. The bone marrow revealed dysplastic features in all three hematopoietic cell lines, and an increase in the monocytic cell line. Based on the features of the bone marrow and the peripheral blood, this case was confirmed to be myelodysplastic syndrome--Chronic myelomonocytic leukaemia (MDS-CMML).

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17611368/