Peer-reviewed veterinary case report
Cat with two types of intestinal lymphoma and treatment outcome
By Sakai, Kosei et al.·Published in The Journal of veterinary medical science·2026·School of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: A feline case of intestinal small T-cell lymphoma with prominent lymphoid follicle formation and concurrent intestinal large B-cell lymphoma.
- Species:
- cat
Plain-English summary
An 11-year-old male mixed-breed cat was brought in after showing signs of lethargy and not eating for two weeks. An ultrasound showed thickening in the intestines and nearby masses, which tests indicated were lymphomas (a type of cancer). The cat underwent surgery to remove the affected tissue, followed by chemotherapy with chlorambucil and prednisolone. Remarkably, the cat lived for over two years after treatment without any signs of the disease returning.
People also search for: cat lymphoma symptoms · cat not eating lethargy · chemotherapy for cat cancer · intestinal cancer in cats · cat surgery recovery time
Abstract
An 11-year-old castrated male mixed-breed cat presented with a 2-week history of lethargy and anorexia. Abdominal ultrasonography revealed jejunal thickening and adjacent masses. As fine-needle aspiration cytology and PCR for antigen receptor gene rearrangement of the masses suggested small T-cell lymphoma, resection biopsy was performed. Based on histopathology and immunohistochemistry, a diagnosis of small T-cell lymphoma with prominent lymphoid follicle formation and concurrent large B-cell lymphoma was made. Postoperative chemotherapy with chlorambucil and prednisolone was performed. The cat survived for 728 days since initial presentation, with no recurrence of clinical signs or ultrasonographic abnormalities. To the best of our knowledge, this is the first report describing a feline case of intestinal small T-cell lymphoma with prominent lymphoid follicle formation and concurrent intestinal large B-cell lymphoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41813183/