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Peer-reviewed veterinary case report

Common causes of uveitis in cats in the UK from 92 cases

By Wegg, Michaela L et al.·Published in Veterinary ophthalmology·2021·Veterinary Vision, United Kingdom·View original on PubMed

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Original publication title: A multicenter retrospective study into endogenous causes of uveitis in cats in the United Kingdom: Ninety two cases.

Species:
cat

Plain-English summary

A group of 92 cats in the UK were diagnosed with uveitis, which is inflammation of the eye, and the most common cause was found to be idiopathic uveitis, meaning the cause was unknown. Other significant causes included feline infectious peritonitis (FIP) and lymphoma. The study noted that male cats were more frequently affected, and purebred cats were more likely to have FIP or lymphoma. Treatment options vary based on the underlying cause, but understanding these common causes can help veterinarians provide better care for affected cats.

People also search for: cat eye problems · uveitis in cats treatment · feline infectious peritonitis symptoms · lymphoma in cats signs

Abstract

PURPOSE: The purpose of this study was to investigate the most common causes of endogenous feline uveitis in a UK referral population and to investigate associations based on signalment. METHODS: Retrospective multicenter cross-sectional study from 2010 to 2019 including cats presented to the Animal Health Trust and the Royal Veterinary College with clinical signs consistent with uveitis. Cats were included in analyzes if they had a full physical examination including an ophthalmic examination, complete blood count, serum biochemistry, and infectious disease testing for at least two diseases unless the diagnosis was found on clinical examination (eg, neoplasia). RESULTS: A total of 92 cats were included in the study. The majority of cats presenting with uveitis were male (66.3%). The most common causes of endogenous uveitis were idiopathic uveitis (42/92 45.7%), feline infectious peritonitis (FIP) 15/92 16.3%), and lymphoma (10/92 10.9%). Fisher's exact test showed differences in breed across diagnosis groups (p&#xa0;=&#xa0;.002) with purebred cats being overrepresented in the lymphoma and FIP groups. Kruskal-Wallis test showed differences in median age across diagnosis groups (p&#xa0;<&#xa0;.001) with cats in the FIP group having the youngest age (median 1.4&#xa0;years, interquartile range (IQR) 0.4-1.8&#xa0;years) and cats in the neoplasia (primary or paraneoplastic) group having the oldest age (median 12.8 IQR 10.8-13.8). Idiopathic uveitis was unilateral in 56.1% of cases, and infectious causes were unilateral in 47.8% of cases. CONCLUSIONS: The most common cause of endogenous uveitis in a population of cats in the UK was idiopathic uveitis, followed by FIP and lymphoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34037308/