Peer-reviewed veterinary case report
Great Dane dog with rare brain tumor causing seizures and surgery
By Majors, Kara et al.·Published in Journal of veterinary internal medicine·2023·Wheat Ridge Animal Hospital, United States·View original on PubMed →
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Original publication title: A novel meningioma with tyrosine-rich crystals in a 6-year-old Great Dane.
- Species:
- dog
Plain-English summary
A 6-year-old female spayed Great Dane started having sudden cluster seizures and was taken to the vet. An MRI revealed a mass in her brain, which was surgically removed. The mass turned out to be a rare type of meningioma (a brain tumor) filled with tyrosine-rich crystals. After surgery, she showed no signs of tumor regrowth and has been seizure-free for 10 months, returning to her normal self.
People also search for: Great Dane seizures · dog brain tumor surgery · meningioma in dogs · cluster seizures in dogs · dog seizure recovery time
Abstract
A 6-year-old female spayed Great Dane was evaluated for acute onset cluster seizures. Magnetic resonance imaging (MRI) identified a mass in the olfactory bulbs with a large mucoid component caudal to the primary mass. The mass was removed via transfrontal craniotomy and histopathology revealed a tyrosine crystalline-rich, fibrous meningioma with a high mitotic index. Repeat MRI at 6 months showed no detectable tumor regrowth. The dog is clinically normal with no seizures at the time of publication 10 months after surgery. This meningioma subtype is rare in humans. This unique meningioma occurred in a dog of younger age and uncommon breed for intracranial meningioma. Biological progression of this tumor subtype is unknown; however, growth rate might be slow despite the high mitotic index.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37312432/