Peer-reviewed veterinary case report
New bone biopsy method improves osteosarcoma diagnosis in dogs
By Neihaus, Steven A et al.·Published in Journal of the American Animal Hospital Association·2011·Affiliated Veterinary Specialists, United States·View original on PubMed →
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Original publication title: A novel method of core aspirate cytology compared to fine-needle aspiration for diagnosing canine osteosarcoma.
- Species:
- dog
Plain-English summary
A group of 27 dogs with bone lesions suspected to be osteosarcoma (a type of bone cancer) underwent two different types of needle tests to help diagnose the condition. The new method, called core aspirate cytology, was compared to the more common fine needle aspiration. Both methods were effective, with core aspirate cytology diagnosing osteosarcoma accurately 95% of the time, while fine needle aspiration was accurate 85% of the time. Additionally, a special stain confirmed the diagnosis with 100% accuracy. Both tests were safe and minimally invasive, making them good options for diagnosing this serious condition in dogs.
People also search for: dog bone cancer symptoms · osteosarcoma diagnosis in dogs · fine needle aspiration vs core aspirate cytology
Abstract
There is little information in veterinary literature regarding the diagnostic accuracy of aspirate cytology for the diagnosis of canine osteosarcoma (OSA). The authors compared the diagnostic accuracy of a novel method of cytologic collection, termed core aspirate cytology (CA), with fine needle aspiration (FNA) and histopathology in 27 dogs with lytic and/or proliferative bone lesions. Alkaline phosphatase (ALP) staining was performed to confirm the diagnosis of OSA cytologically. OSA was accurately diagnosed in 85% and 95% of FNA and CA, respectively. ALP staining was 100% sensitive for the diagnosis of OSA. CA using a bone marrow biopsy needle allowed for penetration of cortical bone and aspirate cytology with a larger bore needle than FNA; however, there was no significant difference in diagnostic accuracy between techniques. Aspirate cytology with ALP staining was a safe, accurate, and minimally invasive diagnostic test for the evaluation of suspected OSA lesions in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21852507/