Peer-reviewed veterinary case report
Dog with bone cancer and muscle weakness improves with prednisone
By Moore, A S et al.·Published in Journal of the American Veterinary Medical Association·1990·Department of Veterinary Surgery, United States·View original on PubMed →
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Original publication title: Osteogenic sarcoma and myasthenia gravis in a dog.
- Species:
- dog
Plain-English summary
A 7-year-old Saint Bernard developed muscle weakness a year after having its right front leg amputated due to bone cancer (osteogenic sarcoma) and receiving chemotherapy. After a thorough examination, the vet diagnosed the dog with myasthenia gravis, a condition that affects muscle control. The dog showed improvement after starting treatment with prednisone, a medication that helps reduce inflammation and improve muscle strength. This case suggests that dogs with osteogenic sarcoma may experience muscle weakness due to myasthenia gravis or similar issues.
People also search for: dog muscle weakness after cancer treatment · Saint Bernard myasthenia gravis symptoms · prednisone for dog muscle problems
Abstract
A 7-year-old Saint Bernard developed muscular weakness 1 year after right forelimb amputation and adjuvant cisplatin chemotherapy for osteogenic sarcoma. Clinical and laboratory findings supported a diagnosis of myasthenia gravis, and the dog had clinical improvement in response to prednisone treatment. Two additional dogs with myasthenia gravis and osteogenic sarcoma were identified by review of the medical records of the University of California Veterinary Medical Teaching Hospital. Findings indicated that myasthenia gravis or other neuromuscular transmission disorders may be associated with muscular weakness in dogs with osteogenic sarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2384323/