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Peer-reviewed veterinary case report

Bone cancer causing swelling in left foot of 4-year-old Great Dane dog

By Liu, S K & Thacher, C·Published in Skeletal radiology·1991·Animal Medical Center, United States·View original on PubMed

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Original publication title: Case report 673: Telangiectic osteogenic sarcoma.

Species:
dog
OsteosarcomaMovement & jointsDogs

Plain-English summary

A 4-year-old male Great Dane was brought in with a painful swelling on his left foot. X-rays showed a serious bone lesion that was filled with blood, and a biopsy revealed it was a type of bone cancer called telangiectatic osteogenic sarcoma. The vet tried to treat it by scraping out the affected bone and adding a bone graft, but the cancer continued to grow. Sadly, the owner decided to euthanize the dog after 10 weeks, as the condition worsened.

People also search for: Great Dane bone cancer symptoms · dog foot swelling treatment · telangiectatic osteogenic sarcoma in dogs

Abstract

A case is presented of a telangiectatic osteogenic sarcoma involving the left third metatarsal of a 4-year-old male Great Dane dog. Radiographs revealed a diaphyseal, expanding, lytic lesion with minimal intralesional sclerosis and a sclerotic rim in the proximal portion. The lesion contained a large amount of blood. The biopsy specimens consisted of spaces which were outlined by fibrous osteoid or granulation tissue. There were islands of multinuclear giant cells and/or fibrous osteoid tissue. A diagnosis of aneurysmal bone cyst was made. The lesion was treated by curettage and insertion of cancellous bone graft but was progressive 10 weeks after treatment. The lesion was further curetted, and these biopsy specimens consisted of aneurysmally dilated spaces and areas of anaplastic sarcomatous cells with mitotic figures and osteoid production, characteristic of telangiectatic osteogenic sarcoma. The dog was euthanized as the owner requested; an autopsy was not performed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1853228/