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Peer-reviewed veterinary case report

Plasma calcium-phosphorus levels predict survival in dogs with kidney

By Lucero, Matías C et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2019·Departamento de Medicina Animal, Spain·View original on PubMed

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Original publication title: A plasma calcium-phosphorus product can be used to predict the lifespan of dogs with chronic kidney disease.

Species:
dog

Plain-English summary

A study looked at how the calcium-phosphorus levels in the blood can help predict how long dogs with chronic kidney disease (CKD) might live. Researchers found that dogs with higher calcium-phosphorus levels (over 70 mg/dL) had a shorter lifespan compared to those with lower levels. For example, dogs with higher levels lived an average of about 45 days, while those with lower levels lived around 505 days. This suggests that measuring calcium and phosphorus in the blood could be a useful way for vets to estimate the prognosis for dogs suffering from CKD.

People also search for: dog chronic kidney disease lifespan · calcium phosphorus levels in dogs · CKD treatment for dogs

Abstract

A serum calcium-phosphorus (sCaPP) product was assessed for prediction of survival in dogs affected with chronic kidney disease (CKD). Dogs (N = 150) were retrospectively studied and followed up to determine their lifespan using 25 healthy dogs as controls. Blood and urine analyses were performed and blood pressure was measured. The dogs were divided into groups according to sCaPP (higher or lower than 70 mg/dL) and International Renal Interest Society (IRIS) stage (IRIS 1-4). Shorter survival was observed with sCaPP > 70 mg/dLcompared to dogs with sCaPP < 70 mg/dL[45.48 days (range: 5.8 to 149 days)505.40 days (range: 113.31 to 539.52 days), mean (95% confidence interval);&#x2264; 0.001 respectively]. Similarly, dogs with advanced IRIS stages showed higher levels of sCaPP [mean (95% confidence interval) in mg/dL; IRIS 1: 42.83 (range: 29.58 to 62.10); IRIS 2: 63.18 (range: 46.34 to 90.09); IRIS 3: 95.57 (range: 88.34 to 127.19); IRIS 4: 130.38 (range: 125.16 to 153.52)], accompanied by lower survival rates. Therefore, sCaPP could represent a valuable tool in the prognosis of canine CKD.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31814639/