Peer-reviewed veterinary case report
New ivermectin treatment plan for dog mange explained
By Mueller, R S & Bettenay, S V·Published in Journal of the American Animal Hospital Association·1999·Animal Skin and Allergy Clinic, Australia·View original on PubMed →
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Original publication title: A proposed new therapeutic protocol for the treatment of canine mange with ivermectin.
- Species:
- dog
Plain-English summary
A group of 222 dogs with mange, either generalized demodicosis or scabies, were treated with a gradually increasing dose of ivermectin, starting from 50 micrograms per kilogram of body weight and reaching 300 micrograms by day five. The treatment continued daily until the skin condition improved for demodicosis, while scabies was treated with doses given four times at weekly intervals. Some dogs experienced mild toxicity but recovered after stopping the medication. The study suggests that careful monitoring and a gradual increase in dosage can help safely treat these skin conditions in dogs.
People also search for: dog mange treatment · ivermectin for dog scabies · how to treat demodicosis in dogs
Abstract
Ivermectin was used orally for the treatment of generalized demodicosis or scabies in 222 dogs. The dose was increased gradually from 50 microg/kg body weight on day one, 100 microg/kg body weight on day two, 150 microg/kg body weight on day three, 200 microg/kg body weight on day four, to the final dose of 300 microg/kg body weight on day five. This dose was continued daily until resolution for demodicosis and given four times at seven-day intervals for scabies. Two patients developed clinical ivermectin toxicity after two and 10 days, respectively, and recovered once the drug was discontinued. A gradual increase of the ivermectin dose into the therapeutic range and thorough monitoring of patients during treatment are recommended when using this drug to treat patients with generalized demodicosis or scabies.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9934933/