Peer-reviewed veterinary case report
Vomiting and weight loss in young dog from rare liver lymphoma
By Chung, Tae-Ho et al.·Published in The Journal of veterinary medical science·2014·Department of Animal Science, South Korea·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: A rare case of hepatic T-cell rich B-cell lymphoma (TCRBCL) in a juvenile dog.
- Species:
- dog
Plain-English summary
A 7-month-old male French Bulldog was brought to the vet after experiencing vomiting, lethargy, loss of appetite, and weight loss over two weeks. Tests including ultrasound and blood work revealed liver problems, and a biopsy confirmed the diagnosis of a rare type of liver cancer called T-cell rich B-cell lymphoma. Unfortunately, despite aggressive chemotherapy treatment, the dog did not respond well and continued to struggle with the disease.
People also search for: dog vomiting and lethargy · French Bulldog liver cancer treatment · juvenile dog weight loss symptoms
Abstract
A 7-month-old castrated male French Bull dog was presented with vomiting, lethargy, anorexia and weight loss of 2 weeks duration. The patient's history and clinical manifestations of suspected hepatopathy were subjected to ultrasonography, radiography, biochemical investigations and cytology of hepatic lesion. The cytologic impression was hepatic lymphoma, which was later confirmed by histopathology. The neoplastic cells were strongly diffusely immunoreactive for PAX5, but not immunoreactive for CD3, and B lymphocyte specific clonal proliferation was detected using by assay of antigen receptor rearrangement. Large numbers of immunoreactive mature non-neoplastic lymphocytes were admixed with the neoplastic cell population. Therefore, the immunohistochemical results were definitively consistent with a T-cell rich B-cell lymphoma (TCRBCL). This is the first description of a hepatic TCRBCL in a juvenile dog showing a poor response to aggressive chemotherapy.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25283946/