Peer-reviewed veterinary case report
Oral tumors in Swiss cats are mostly squamous cell carcinoma
By Gasymova, Eva E et al.·Published in American journal of veterinary research·2025·Department of Dentistry and Oral Surgery·View original on PubMed →
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Original publication title: A retrospective study of oral tumors in cats in Switzerland identifies squamous cell carcinoma as the predominant tumor type.
- Species:
- cat
Plain-English summary
A study found that squamous cell carcinoma, a type of cancer, is the most common oral tumor in cats, particularly affecting older cats around 13 years old. Out of 294 cases examined, 82% were malignant tumors, with many located on the tongue. Symptoms pet owners might notice include mouth sores or difficulty eating. Early detection is crucial, as these tumors can be aggressive. Treatment options may include surgery or other therapies, but the study highlights the importance of regular veterinary check-ups for older cats to catch these issues early.
People also search for: cat oral tumor symptoms · squamous cell carcinoma in cats · older cat mouth sores · cat cancer treatment options
Abstract
OBJECTIVE: The study investigated the distribution, types, and geographic distribution of oral tumors in cats in Switzerland, providing insights into demographics, tumor features, and emerging trends. METHODS: We analyzed pathology records of oral tumors in cats diagnosed between 2012 and 2022 from diagnostic laboratories in Switzerland. Only histologically confirmed neoplasms were included; inflammatory and cystic lesions were excluded. Geographic distributions were assessed using postal addresses. RESULTS: Among 339 reports of oral tumors in cats, 294 met inclusion criteria. Malignant tumors dominated 82.0% (241 of 294), with squamous cell carcinoma most prevalent (70.5% [170 of 241]), followed by fibrosarcoma (7.2% [19 of 241]), melanoma (4.6% [11 of 241]), and adenocarcinoma (4.6% [11 of 241]). Benign tumors represented 18.0% (53 of 294), mostly with peripheral odontogenic fibroma (8.2% [24 of 294]). Squamous cell carcinoma was commonly located on the tongue (24.0% [33 of 137]), accounting for all tumors identified in the sublingual region (100% [17 of 17]). Peripheral odontogenic fibroma occurred mainly in caudal mandibles (41.7% [10 of 24]). Histopathologic analysis revealed that ulceration and necrosis were frequent in malignant cases, with a broader range and higher mitotic indices (P < .0001). The European Shorthair was the most commonly represented breed (80.6% [237 of 294]), and older cats (median age 13 years) were most affected. CONCLUSIONS: The results emphasize the high frequency of malignant oral tumors, particularly squamous cell carcinoma, in cats in Switzerland, consistent with trends observed in other regions, and identified distinct histopathologic characteristics differentiating malignant from benign cases. CLINICAL RELEVANCE: Investigating the prevalence, types, and geographic distribution of oral tumors in cats in Switzerland may support awareness, early detection, accurate diagnosis, and potentially better clinical outcomes.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40744111/