Peer-reviewed veterinary case report
Use of acepromazine in dogs with seizures and effects seen
By Tobias, Karen M et al.·Published in Journal of the American Animal Hospital Association·2006·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: A retrospective study on the use of acepromazine maleate in dogs with seizures.
- Species:
- dog
Plain-English summary
A group of dogs with a history of seizures were given a tranquilizer called acepromazine to see if it could help manage their seizures. Surprisingly, none of the 36 dogs given the medication for calming down had any seizures within 16 hours. For the 10 dogs that were actively seizing, acepromazine helped stop their seizures for up to 8 hours, and one dog even had fewer seizures for two months after treatment. This suggests that acepromazine might be useful in certain situations for dogs with seizures, despite previous concerns.
People also search for: dog seizures treatment · acepromazine for dogs · managing dog seizures · tranquilizer for dogs with seizures · why is my dog having seizures
Abstract
Use of acepromazine (i.e., acetylpromazine) maleate in dogs with a history of seizures is reportedly contraindicated because of the risk of decreasing the seizure threshold in these animals. In this retrospective study, acepromazine was administered for tranquilization to 36 dogs with a prior history of seizures and to decrease seizure activity in 11 dogs. No seizures were seen within 16 hours of acepromazine administration in the 36 dogs that received the drug for tranquilization during hospitalization. After acepromazine administration, seizures abated for 1.5 to 8 hours (n=6) or did not recur (n=2) in eight of 10 dogs that were actively seizing. Excitement-induced seizure frequency was reduced for 2 months in one dog.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16822767/