Peer-reviewed veterinary case report
Cat colon cancer treated with surgery and carboplatin chemotherapy
By Arteaga, Theresa A et al.·Published in Journal of the American Animal Hospital Association·2012·Pacific Veterinary Specialists, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: A review of 18 cases of feline colonic adenocarcinoma treated with subtotal colectomies and adjuvant carboplatin.
- Species:
- cat
Plain-English summary
A group of 18 cats diagnosed with colonic adenocarcinoma (a type of cancer in the colon) underwent surgery to remove part of their colon, followed by chemotherapy with a drug called carboplatin. The cats received an average of five doses of carboplatin, and the treatment was generally well-tolerated with few side effects. Cats that had weight loss as a symptom before treatment tended to do better, while those with cancer spread to lymph nodes or other areas had shorter survival times. Overall, the surgery combined with chemotherapy showed promise, with some cats living for over 500 days after treatment.
People also search for: cat colon cancer treatment · feline adenocarcinoma surgery · carboplatin for cats cancer
Abstract
Feline colonic adenocarcinoma is a locally invasive, highly metastatic tumor that is most often treated with wide surgical excision (subtotal colectomy) and systemic chemotherapy either with or without nonsteroidal anti-inflammatory medications. In this retrospective study, the outcome of subtotal colectomy and adjuvant carboplatin in 18 client-owned cats is described. The median carboplatin dose was 200 mg/m(2) (range, 200-254 mg/m(2)) q 4 wk with a median of five doses/cat (range was two to seven doses/cat). Limited toxicities were noted. Positive prognostic factors for the disease-free interval included cats that had weight loss as a presenting sign (P < 0.036) and negative prognostic factors for median survival included nodal and distant metastasis (178 versus 328 days and 200 versus 340 days, respectively). The median disease-free interval was 251 days (range, 37-528 days) and the median survival time was 269 days (range, 40-533 days). Subtotal colectomy and adjuvant carboplatin is a safe and potentially effective treatment for cats with colonic adenocarcinoma.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23033464/