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Peer-reviewed veterinary case report

Abnormal motor activity during anaesthesia in a dog: a case report

Journal:
Acta Veterinaria Scandinavica
Year:
2010
Authors:
A. Lervik et al.
Species:
dog

Plain-English summary

This case report discusses a four-year-old male Bernese mountain dog that experienced convulsions during anesthesia. The dog was given a combination of medications, including acepromazine, methadone, propofol, and ketamine, but had no prior history of seizures. Since multiple drugs were used, it’s hard to pinpoint which one might have caused the convulsions. Overall, the report highlights that such events during anesthesia are rare and not well understood in veterinary medicine.

Abstract

Seizures or convulsions that occur during anaesthesia in veterinary patients are infrequently reported in the literature. Consequently, the incidence of such events is unknown. Several drugs commonly used in clinical veterinary anaesthesia have been shown to induce epileptiform activity in both human clinical patients and experimental candidates. The present case report describes convulsions in a four-year old male Bernese mountain dog during maintenance of anaesthesia with isoflurane after premedication with acepromazine and methadone followed by co-induction with propofol and ketamine. The dog had no history of previous convulsions. The use of several sedative and anaesthetic drugs makes it difficult to find one single causative pharmaceutical.

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Original publication: https://www.semanticscholar.org/paper/21118580