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Peer-reviewed veterinary case report

Accidental afloqualone intoxication in two dogs.

Journal:
The Journal of veterinary medical science
Year:
2018
Authors:
Ahn, Jin-Ok et al.
Affiliation:
Department of Veterinary Internal Medicine and Institute of Veterinary Science · South Korea
Species:
dog

Abstract

Two dogs presented to the emergency service after accidental ingestion of afloqualone tablets, a muscle relaxant used for back pain in humans. Toxic effects of the drug in these dogs included vomiting, respiratory depression, seizures, ataxia, bradycardia, and hematuria. Treatment consisted of fluid diuresis, furosemide, and propofol. Flumazenil, a gamma-amino butyric acid antagonist, was administered intravenously; however, it was not effective in stopping the seizures in these dogs. Both dogs recovered with supportive treatment. To the authors' knowledge, this is the first documented report of afloqualone intoxication in dogs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/29142147/