Peer-reviewed veterinary case report
How accurate is CT at measuring bone cancer size in dogs
By Karnik, Ketaki S et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2012·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Accuracy of computed tomography in determining lesion size in canine appendicular osteosarcoma.
- Species:
- dog
Plain-English summary
A group of 10 dogs with appendicular osteosarcoma (a type of bone cancer) underwent a special CT scan to measure the size of their tumors. The scans were compared to actual tumor sizes found during surgery. The CT scans were generally accurate, especially for measuring the tumor inside the bone, but they tended to overestimate the size of the tumor by about 1.8%. This information can help veterinarians determine if a dog is a good candidate for limb-sparing surgery.
People also search for: dog osteosarcoma treatment · CT scan for dog cancer · measuring tumor size in dogs
Abstract
Multidetector contrast enhanced computed tomography with acquisition of 0.625-mm thick transverse images was used to measure the extent of appendicular osteosarcoma in 10 dogs. The measured length of tumor based on CT was compared to the true length of tumor using histopathology. There was a statistically significant association with good correlation between the true length of osteosarcoma compared to the length of intramedullary/endosteal abnormalities on CT with a mean overestimation of 1.8% (SD = 15%). There was not a statistically significant association between the true tumor length and the length of periosteal proliferation on CT with a mean overestimation of 9.7% (SD = 30.3%). There was a statistically significant association, but with poor correlation, between the true tumor length compared to the length of abnormal contrast enhancement with a mean overestimation of 9.6% (SD = 34.8%). The extent of intramedullary/endosteal CT abnormalities assessed from submillimeter transverse images may be of value in assessing patient candidacy and surgical margins for limb-sparing surgery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22413965/