Peer-reviewed veterinary case report
Acquired multiple acyl-CoA dehydrogenase deficiency and marked selenium deficiency causing severe rhabdomyolysis in a horse.
- Journal:
- The Canadian veterinary journal = La revue veterinaire canadienne
- Year:
- 2015
- Authors:
- Gomez, Diego E et al.
- Affiliation:
- Department of Health Management (Gomez · United States
- Species:
- horse
Plain-English summary
This report discusses a pregnant mare that experienced severe muscle breakdown, known as rhabdomyolysis, which was linked to a lack of selenium, an important nutrient, and a condition called acquired multiple acyl-CoA dehydrogenase deficiency (MADD) caused by seasonal pasture myopathy (SPM). The findings suggest that checking the mare's selenium levels is crucial when she shows signs of pasture myopathy, as low selenium could make her condition worse. The case emphasizes the need for careful monitoring of nutrient levels in horses that are affected by these issues.
Abstract
This report describes a case of severe rhabdomyolysis in a pregnant mare associated with histopathologic and biochemical features of both selenium deficiency and acquired multiple acyl-CoA dehydrogenase deficiency (MADD) due to seasonal pasture myopathy (SPM). This case highlights the importance of assessing plasma selenium levels in horses with clinical signs of pasture myopathy as this deficiency may be a contributing or exacerbating factor.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26538673/