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Peer-reviewed veterinary case report

Dog with sudden face nerve damage linked to nervous system lymphoma

By Pfaff, A M et al.·Published in Journal of the American Animal Hospital Association·2000·Department of Veterinary Clinical Sciences, United States·View original on PubMed

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Original publication title: Acute bilateral trigeminal neuropathy associated with nervous system lymphosarcoma in a dog.

Species:
dog
LymphomaBrain & nervesDogs

Plain-English summary

A 9-year-old dog showed signs of facial weakness and difficulty eating due to a condition called bilateral trigeminal neuropathy, which affects the nerves responsible for sensation in the face. After testing, the vet found that the dog had multicentric lymphoma, a type of cancer that was affecting the nervous system. The diagnosis was confirmed through a spinal fluid test and muscle activity tests. Unfortunately, the cancer had invaded the nerves, leading to the symptoms. Treatment options would typically include chemotherapy, but the specific outcome for this dog isn’t detailed.

People also search for: dog facial weakness · lymphoma in dogs · trigeminal neuropathy treatment for dogs

Abstract

A nine-year-old dog presented with clinical signs consistent with bilateral trigeminal neuropathy. Multicentric lymphoma was diagnosed, and neoplastic lymphocytes were identified in the cerebrospinal fluid. Electromyography revealed spontaneous activity in temporal and masseter muscles. Histopathological examination demonstrated neoplastic cell invasion of temporal and masseter myofibers and of multiple peripheral nerves, including the trigeminal nerve. Central nervous system pathology consisted primarily of spinal root and leptomeningeal lymphoid cell infiltration with relative sparing of spinal cord and brain parenchyma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10667407/