Peer-reviewed veterinary case report
Acute monoblastic leukemia in a cat without feline leukemia virus
By Tagawa, Michihito et al.·Published in The Journal of veterinary medical science·2020·Obihiro University of Agriculture and Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Acute monoblastic leukemia in a feline leukemia virus-negative cat.
- Species:
- cat
Plain-English summary
A 12-year-old female domestic short-haired cat was brought in because she was losing weight, not eating, and having trouble breathing. Blood tests showed she had severe anemia and a high number of abnormal white blood cells, indicating acute myeloid leukemia. Despite treatment with chemotherapy drugs and steroids, her condition did not improve without a blood transfusion, which the owner chose not to pursue. Sadly, after two months of treatment, the cat passed away.
People also search for: cat weight loss and not eating · cat breathing problems · acute myeloid leukemia treatment in cats
Abstract
A 12-year-old female domestic short-haired cat was presented due to weight loss, anorexia, and tachypnea. Complete blood count revealed severe anemia, leukocytosis with massive undifferentiated blast cells, and thrombocytopenia. Bone marrow aspiration showed acute myeloid leukemia, subclassified as monoblastic leukemia (M5a) based on the outcomes of the cytochemistry examinations. The SNAP feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) test using whole blood was negative. In addition, FeLV/FIV proviral polymerase chain reaction test using bone marrow aspirate was also negative. Although the cat was treated with doxorubicin, cytosine arabinoside, and prednisolone, anemia did not improve without blood transfusion. The owner declined further treatment after 2 months, and the cat died a few days later.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32448817/