Peer-reviewed veterinary case report
Cat with acute myelomonocytic leukemia had brief remission
By Mylonakis, M E et al.·Published in Australian veterinary journal·2008·Companion Animal Clinic·View original on PubMed →
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Original publication title: Acute myelomonocytic leukaemia with short-term spontaneous remission in a cat.
- Species:
- cat
Plain-English summary
A 2-year-old spayed female domestic shorthair cat was brought to the vet because she had stopped eating and seemed very tired for a week. The vet found that she had a fever, an enlarged spleen, and mouth sores, and tests showed she had a type of blood cancer called acute myelomonocytic leukaemia. Surprisingly, the cat experienced a short period of improvement without any treatment, lasting about a month, but unfortunately, she relapsed and passed away a week later.
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Abstract
A 2-year-old, spayed female domestic shorthair cat was referred with a history of anorexia and depression of 1 week duration. On physical examination, the cat was lethargic and febrile, with splenomegaly, anisocoria and ulcerative stomatitis. A complete blood count (CBC) and a biochemistry profile showed leukocytosis, numerous blast cells in the peripheral blood, thrombocytopenia, hyperglobulinaemia and a positive test for feline leukaemia virus antigen. A diagnosis of acute myelomonocytic leukaemia was made on the basis of the results of bone marrow cytology, histopathology, and immunochemistry (CD3, CD79a, lysozyme, and myeloperoxidase) tests. Following an unexpected 1-month period of clinical and clinicopathological remission without chemotherapy, the cat relapsed and died 1 week later.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18498558/