Peer-reviewed veterinary case report
Dog with spinal cord tumor from acute myelomonocytic leukemia
By Hayashi, Akiyoshi et al.·Published in The Journal of veterinary medical science·2011·Nakayama Veterinary Hospital·View original on PubMed →
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Original publication title: Acute myelomonocytic leukemia (AML-M4) in a dog with the extradural lesion.
- Species:
- dog
Plain-English summary
A 2-year-old dog was brought in with neurological problems and a high white blood cell count. Tests showed the presence of abnormal cells in the blood and bone marrow, leading to a diagnosis of acute myelomonocytic leukemia (AML-M4). Despite receiving a combination of chemotherapy, the dog's condition worsened, and the neurological issues continued to progress. Unfortunately, the dog was euthanized, and further examinations revealed a tumor caused by the leukemia that was pressing on the spinal cord, contributing to the symptoms.
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Abstract
A two-year-old dog having presented with neurological signs showed marked leukocytosis and appearance of blast cells in the peripheral blood. Hematological and bone marrow examination showed an increase in blasts having both myeloid and monocytic cells characteristics. The dog was diagnosed with acute myelomonocytic leukemia (AML-M4) on the basis of bone marrow findings. Although the dog was treated with a multi-combination chemotherapy, the neurological abnormalities progressed and the dog was euthanized. Myelographic examination and necropsy revealed the extradural lesion formed by AML-M4 around the cervical spinal cord and this lesion was considered as a cause of the neurological signs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21060242/